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(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase : ウィキペディア英語版 | (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase (, ''uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase'', ''ganglioside GM2 synthase'', ''ganglioside GM3 acetylgalactosaminyltransferase'', ''GM2 synthase'', ''UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase'', ''UDP-N-acetyl-D-galactosamine:1-O-()-ceramide 1,4-beta-N-acetyl-D-galactosaminyltransferase acetylgalactosaminyltransferase'', ''UDP-N-acetylgalactosamine GM3 N-acetylgalactosaminyltransferase'', ''uridine diphosphoacetylgalactosamine-acetylneuraminylgalactosylglucosylceramide acetylgalactosaminyltransferase'', ''uridine diphosphoacetylgalactosamine-hematoside acetylgalactosaminyltransferase'', ''GM2/GD2-synthase'', ''beta-1,4N-aetylgalactosaminyltransferase'', ''asialo-GM2 synthase'', ''GalNAc-T'', ''UDP-N-acetyl-D-galactosamine:(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetyl-D-galactosaminyltransferase'') is an enzyme with system name ''UDP-N-acetyl-D-galactosamine:1-O-(O-(N-acetyl-alpha-neuraminyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl)-ceramide 4-beta-N-acetyl-D-galactosaminyltransferase''. This enzyme catalyses the following chemical reaction : UDP-N-acetyl-D-galactosamine + 1-O-()-ceramide UDP + 1-O--ceramide This enzyme catalyses the formation of the gangliosides (i.e. sialic-acid-containing glycosphingolipids) GM2, GD2 and SM2 from GM3, GD3 and SM3, respectively. == References ==
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